Methionine Capped Nanoparticles as Acetylcholinesterase Inhibitors

نویسندگان

چکیده

The Cover Feature shows a metal nanoparticle modified with the amino acid L-methionine and adsorption of enzyme acetylcholinesterase (AChE) on methionine-capped surface. Methionine-capped Ag Au nanoparticles (NPs) were tested as inhibitors AChE, they showed moderate inhibitory potential toward AChE. NPs are much larger than molecules cannot enter active site gorge, so inhibition occurs by blockage enzyme's due to AChE surface NPs. have be further investigated for use in treatment cognitive impairment accompanying depression Alzheimer's disease. We want thank Prof. Igor Pašti graphic design. More information can found Research Article B. Laban co-workers.

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ژورنال

عنوان ژورنال: European Journal of Inorganic Chemistry

سال: 2023

ISSN: ['1434-1948', '1099-0682']

DOI: https://doi.org/10.1002/ejic.202300151